Rough Endoplasmic Reticulum (RER)
- The Rough Endoplasmic Reticulum (RER) is a network of flattened, stacked sacs and tubules that are located near the nucleus in eukaryotic cells.
- It is called “Rough” because it has many ribosomes attached to its surface, which gives it a granular appearance under a microscope.
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5 Important Functions Of Rough Endoplasmic Reticulum are as follows –
- Protein synthesis
The Rough Endoplasmic Reticulum (RER) is the site of protein synthesis in eukaryotic cells. Ribosomes bind to the RER and use the information in the mRNA to synthesize new proteins. These proteins are then transported to the lumen of the RER for further processing and modification.
- Protein folding
Once the protein is synthesized, it needs to be folded into its correct conformation in order to function properly. The Rough Endoplasmic Reticulum (RER) is equipped with a variety of groups of proteins and other molecules that help the protein fold into its correct shape.
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- Protein modification
Proteins are often modified after they are synthesized in order to make them functional. Rough Endoplasmic Reticulum (RER) is the site of many of these modifications, such as the addition of sugars or lipids to the protein.
- Protein transport
Rough Endoplasmic Reticulum (RER) is also responsible for transporting proteins to different destinations within the cell. Proteins that are destined for the plasma membrane, secretory vesicles, or lysosomes are transported out of the RER through vesicles that bud off from the Rough Endoplasmic Reticulum (RER) and are transported to their destinations via the Golgi apparatus.
Rough Endoplasmic Reticulum (RER) is involved in cell signaling, which is the process by which cells communicate with each other. Rough Endoplasmic Reticulum (RER) can release signals, such as hormones and growth factors, which can stimulate or inhibit other cells.
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